International Trends in Immunity
نویسندگان
چکیده
HIV infection represents a risk factor for hypersensitivity reactions to antimicrobial drugs. We report the first case of delayed, cell-mediated, allergy to isoniazid in a 57-year-old HIV-infected patient, who developed a maculo-papular exhantema after 10-day treatment with isoniazid etambutol, pyrazinamide and rifabutin. Pacht test resulted positive for isoniazid. Graded challenges with the other aforementioned medications were performed, allowing the patient to complete the antitubercular treatment. The striking obvervation of this case is that the patient developed a cell-mediated hypersensitivity despite the low level of CD4+ T cell count (< 200 cells/μL).
منابع مشابه
Exercising FOREIGN CRIMINAL JURISDICTION over State officials
Our article examines the extent to which state officials are subject to prosecution in foreign domestic courts for international crimes. We consider the different types of immunity that international law accords to state officials, the reasons for the conferment of this immunity and whether they apply in cases in which it is alleged that the official has committed an international crime. ...
متن کاملThe Role of Integrin Expressing Cells in Modulating Disease Susceptibility and Progression (January 2016).
In this review we have summarized the role of gut homing molecules with a focus on the heterodimeric integrin α4β7 since the α4β7 has been shown to be important in modulating SIV transmission, disease susceptibility and progression. This review provides an overview of integrins, their structure and function to provide a general background upon which the role of the α4β7 integrin can best be und...
متن کاملInternational Trends in Immunity
Although a relationship between inflammation and some cancers is well-established, the complex role of the complement system in cancer development remains incompletely understood. The studies that have investigated this relationship have primarily reported that the diverse components of the complement system support tumor growth. However, some studies have demonstrated that components of the co...
متن کاملRubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis
Background: Rubella infection with in the first trimester of pregnancy may lead to adverse pregnancy outcomes. The present study was conducted to evaluate the immunity against rubella among pregnant Iranian women. Materials and Methods: The steps of meta-analyses were conducted based on the PRISMA guidelines. To review the associated English and Persian literature, a comprehensive search was co...
متن کاملI-22: The Process for Justification of ARTs in Iran Health System: Ethical and Legal Trends
-
متن کاملUnanswered questions from the international trends in hospital bed occupancy and its potential impact on hospital planning
The ongoing rise in medical emergency admissions seen around the world over the past four to five decades has never been fully explained. Long term trends in hospital bed occupancy in England, Canada and Australia are examined to show that a recurring pattern of time-specific increases appears to apply. The possibility of a common infectious source is discussed. Whatever the cause the needs to ...
متن کامل